Ceftriaxone

• Adult/child >12 yr: IM/IV 1-2 g/day, max 4 g/24 hr

• Child ≤12 yr: IM/IV 50-75 mg/kg/day in equal doses q12-24hr

Pneumonia, Hospital-acquired pneumonia Intra-abdominal infections, Complicated urinary-tract infections (UTI), Acute exacerbations of chronic obstructive pulmonary disease. IV injection or IV infusion, Adult: 1–2g once daily, 2g dose to be used for hospital-acquired pneumonia and severe cases Cellulitis, Erysipelas Moderate diabetic foot infection mild or leg ulceration or Severe, diabetic. IV injection or IV infusion Adult: 2g once daily Prophylaxis of infection from human bites in combination with other drugs, Prophylaxis of infection from animal bites in combination with other drugs, Treatment of infection from human bites in combination with other drugs IV injection or IV infusion Adult: 2goncedaily Complicated skin and soft tissue infections, infection of bones and joints IV injection or IV infusion Adult: 2g once daily Suspected bacterial infection in neutropenic patients IV injection or IV infusion Adult:  2–4g daily, dose at higher end of the recommended rang used in severe cases Bacterial meningitis Bacterial endocarditis IV injection or IV infusion Adult:  2–4g daily, doses at the higher end of the recommended range used in severe cases Child1month–11years (body-weight up to50 kg): 80–100mg/kg once daily,100mg/kg once daily dose should be used for bacterial endo carditis; maximum 4g per day Child 9–11years(body-weight 50kg and above): 2–4g once daily, doses at the higher end of the Child12–17years: 2–4g once daily, doses at the higher end of the recommended range used in severe cases IV injection Child 9–11years (body-weight50kg and above): 2–4g once daily, doses at the higher end of the recommended range used in severe cases ;doses of 50mg/kg or more should be given by infusion Child12–17years: 2–4g once daily, doses at the higher end of the recommended range used in severe cases IM injection Child1month to 11years (body-weight up to 50kg): 80–100mg/kg daily,100mg/kg daily dose should be used for bacterial endocarditis; maximum 4g / day Child 9–11years (body-weight 50kg and above): 2–4g daily, doses at the higher end of the recommended range used in severe cases Child12–17years: 2–4g daily, doses at the higher end of the recommended range used in severe cases Surgical prophylaxis IV injection or IV infusion Adult:  2g for1dose, dose to be administered 30–90 minutes before procedure Pelvic inflammatory disease Deep IM injection Adult:  500mg 1dose Gonococcal conjunctivitis Uncomplicated gonorrhea anogenital and pharyngeal infection, when sensitivity unknown By Deep IM Injection Adult: 1g for 1dose   Gonococcal epididymo-orchitis By Deep IM Injection Adult: 1g for 1dose, to be followed by an additional anti-bacterial course to treat epididymo-orchitis Syphilis Deep IM injection Adult: 0.5–1g once daily for 10–14 days, increased to 2g once daily for neuro Syphilis Lyme disease affecting CNS. IV injection or IV infusion Adult:  2g twice daily for 21days, alternatively 4g once daily for 21days Lyme arthritis Acrodermatitis chronic atrophicans IV injection or IV infusion Adult:  2g once daily for 28 days Lymecarditis IV injection or IV infusion Adult:  2g once daily for 21days Prevention of secondary case of meningococcal meningitis By IM injection Adult: 250mg for1dose. Prevention of secondary case of Haemophiles influenzae type B disease By IM injection, or by IV Injection, or by IV infusion ▶ Adult: 1g daily for 2 days.  Acute otitis media By Deep IM Injection Adult: 1–2g for1dose, dose can be given for 3 days if severely ill or previous therapy failed Acute prostatitis By Slow IV Injection, or By IV infusion Adult: 2g once daily